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Image Search Results
Journal: Oncology reports
Article Title: Increased expression and activity of p75NTR are crucial events in azacitidine-induced cell death in prostate cancer.
doi: 10.3892/or.2016.4832
Figure Lengend Snippet: Figure 1. Antiproliferative and pro-apoptotic effects induced by azacitidine (5Aza-CR) at different concentrations in the presence or not of 10 ng/ml NGF. (A) (PC3) and (B) (22rv1) cells are subjected to the cytotoxic effects of different doses of azacitidine with or without NGF. (C) (PC3) and (D) (22rv1) cells undergo time-dependent apoptosis after treatment with a non-toxic concentration (0.5 µM) of azacitidine in combination with NGF. Data are representative of three independent replicates.
Article Snippet: Two
Techniques: Concentration Assay
Journal: Oncology reports
Article Title: Increased expression and activity of p75NTR are crucial events in azacitidine-induced cell death in prostate cancer.
doi: 10.3892/or.2016.4832
Figure Lengend Snippet: Figure 2. Western blot analyses show a time-dependent induction of p75NTR and AR, but not TrkA expression, after in vitro administration of 0.5 µM azacitidine (Aza-CR) in PC3 (A) and 22rv1. (C) Immunocytochemical expression of p75NTR and AR in 22rv1 cells. (D) PC3 and (E) 22rv1 cells were examined for expres- sion levels of downstream components proximal to p75NTR (TRADD, RIP, DR4, DR5 and TRAF2) after treatment with 0-5 µM azacitdine and 10 ng/ml NGF. (F) Immunohistochemical evaluation of p75NTR, TRADD and TRAL-R (DR4) in PC3 cell tumor-bearing nude mice treated or not with azacitidine (Vidaza 0.8 mg/kg/7 consecutive days). Each lane was loaded with 100 µg of proteins from the cell extracts obtained from the control and treated cells.
Article Snippet: Two
Techniques: Western Blot, Expressing, In Vitro, Immunohistochemical staining, Control